Cortisol
Cortisol is a very important hormone that’s for sure. It is produced by the adrenal glands and is often called the ‘stress hormone’ because it responds to stress, either physical or emotional. Cortisol helps control inflammation, makes glucose available by breaking down muscle to amino acids, suppresses the immune system and is likely to enhance fat storage at the expense of protein and muscle. Cortisol rises when blood glucose gets low : in the early morning and during exercise, especially prolonged endurance exercise. Cortisol is a catabolic hormone. In manufactured form it’s called hydrocortisone or cortisone.
Epinephrine (Trade Name Adrenaline)
We all know it as adrenaline but epinephrine is considered the ‘fight and flight’ hormone because it acts quickly on cue to constrict arteries and raise blood pressure and dilate the airways to enable your heart to beat faster and you to breathe more efficiently – all of which are important if you suddenly need to run away from an attacking lion! As well, epinephrine elicits the muscles and liver to give up stored glucose (glycogen) so that you have instant energy to fuel that survival run. In this sense epinephrine is a catabolic hormone like cortisol.
Glucagon
Glucagon could be considered a mirror hormone of insulin. When you fast or eat a low-carb diet glucagon will be more active than insulin because of low blood glucose. Glucagon tells the liver to give up its glucose stores to the bloodstream and also to break down those amino acids from muscle that cortisol sent to the liver to make more glucose. If insulin is an anabolic hormone then glucagon is a catabolic hormone.
Natural Anabolic Enhancement
I trust the bigger picture of hormone action and metabolism is starting to make sense. You can see from the discussion so far that we have a task ahead of us here. We want to keep those anabolic hormones high and the catabolic hormones as low as possible while still providing basic functionality. It's not useful to regard cortisol or any other hormones as 'bad guys' because we couldn't live without them.
In the ‘natural’ bodybuilding movement and for sports where compliance with drug-testing protocols is essential for competition legality, finding a way of training or eating that will maximize or enhance testosterone and androgen-related muscle and strength is keenly sought. Alas, this is not a process that is easily manipulated and there is much still to learn. However, that has not stopped supplement manufacturers claiming to have products that can do just that with herbal extracts or combinations of vitamins or ‘legal’ steroids. Examples of such products are the herb Tribulus terrestris, zinc-magnesium tablets, ginseng, bovine colostrum, beta-alanine, HMB, and DHEA, a prohormone banned in most sports but not in baseball. Tribulus has become popular in the bodybuilding community even though there is no evidence that it provides any advantage.
A recent study of elite rugby players published in the May 2007 issue of the Journal of Strength and Conditioning Research did not find any advantage in muscle enhancement or performance from supplementation with Tribulus. This seems to confirm the result of previous studies. There are no specific non-food supplements other than creatine that have been shown to enhance bulk and training similar to the anabolic steroids -- and creatine is a component of meat foods. Yet even creatine has an uneven performance as a supplement.
What You Can do to Enhance Muscle-Building Hormones Naturally
Here are several approaches to diet and training that can go some way toward maximizing your anabolic hormone response and building and protecting muscle mass and strength. Although the following is based on recent research results, there is still much to learn about the complex web of hormone interactions involved in strength and muscle enhancement, so don’t be too surprised if something changes soon.
Pre- and post-exercise nutrition. Consume about 20 grams of protein in an easily digested source up to 45 minutes before a workout. Skim milk with a little sugar will do fine. About 20 fluid ounces (600 mls) or a little less is about right. Sip a sports drink during the workout at regular intervals, especially if you go beyond 60 minutes. Within 30 minutes of finishing the workout consume another 20 grams of protein with about 40 grams of carbohydrate. Again, skim milk seems to work well. Choose your favorite protein-carb powder or even a commercial flavored milk if you prefer. Increase the carbs up to about 3 or 4:1 carbs to protein ratio if you’ve had a heavy or long session with cardio or intervals or circuit.
Taking carbohydrate during exercise has been shown to minimize the rise in cortisol (Bird 2006). Testosterone, growth hormone, epinephrine and cortisol all increase during exercise with intensity. With blood glucose topped up, cortisol doesn’t get the signal to supply glucose, so muscle doesn’t get burned up in the process. Even after your session, testosterone and cortisol levels move around quite a bit and testosterone levels may drop. The testosterone to cortisol ratio is the key. Keeping testosterone as high as possible and cortisol as low as possible when you don't need it is to your advantage.
It's worth stating that you don't need any cortisol-reducing supplement tablets. There is no proof that they work and carbohydrate manipulation seems to do the job for little added cost.
